Teens Find Drought and Zika Remedies

Entering contests and writing to potential mentors not only can help individual students jump start their own careers but these proactive efforts also can help humanity. Dr. Hongjun Song, the mentor who received a letter from the student involved in Zika virus research, observed: "Unencumbered by previous experience, high school students aren't afraid of failure and are freer to try things than graduate students or postdocs."

Help for drought-starved crops

Kiara Nirghin, the 16-year-old South African girl who won the grand prize in Google's Science Fair (googlesciencefair.com), reasoned that a superabsorbent polymer (SAP) used in diapers could help soil retain more water when drought threatens crops. To avoid the pricey, less eco-friendly acrylic acid chemicals used in current SAPs, Ms. Nirghin tried creating a SAP by applying UV light and heat to avocado and orange peels. When sprinkled on fields, her polymer, which holds 300 times its weight in liquid, provides water for crops that would otherwise die from drought.
(Kiara Nirghin is among the world's 30 most influential teens TIME magazine lists at time.com/teens2016.)

Help for studying the Zika virus

At the University of Pennsylvania's School of Engineering and Applied Science, engineers developed a $2 genetic test to detect the Zika virus immediately by using color-changing dye in a device about the size of a soda can. The process requires no electricity or extensive technical training.
     Chris Hadiono, whose parents are U.S. immigrants from Indonesia, was a high school intern at Dr. Hongjun Song's neurology lab at John Hopkins University, when he developed a bioreactor device used to determine how the Zika virus causes the abnormal brain development which results in the small heads of newborn babies, i.e. microcephly, and many more problems.
     Using 3D printing instructions from a YouTube tutorial, Hadiono created a machine with gears that keep 12 "mini-brains" floating and growing in wells, each filled with about one teaspoon of nutrient rich liquid, by constantly stirring the liquid in all the wells at the same time.
     Before Hadiono's contribution, the neural tissue of human brains, "mini-brains," already could be produced by turning human skin cells (3D printers also can create human tissue and bone) into stem cells which could be turned into the neural stem cells that became human neural brain tissue resembling the human cerebral cortex affected by the Zika virus. And a magnetic bar could continuously stir a rich nutrient broth-like medium, or liquid, that enabled "mini-brains" to float and grow in all directions. The problem was the big device required too much costly medium and could only be used once to accommodate a few experiments at a time. With Hadiono's bioreactor device, at a much lower cost, researchers can see how the Zika virus infects and kills neural stem cells in 12 different parts of a human's cerebral cortex at the same time..  With the work of another teen, maybe prevention and a cure for microcephly will not be far behind.